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KMID : 0376219860230010189
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Chonnam Medical Journal
1986 Volume.23 No. 1 p.189 ~ p.197
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Effects of the Cervical Sympathetic Stimulation on the Submaxillary and Parotid Secretion in Cats
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Abstract
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It has been generally known that stimulation of the parasympathetic and sympathetic nerves produce serectory response together to the submaxillary gland, although there are evidences of inhibitory effect of the sympathetic for the gland. If both nerves are able to affect the serectory response, the physiological significance of the autonomic enervation of the gland becomes obscure. In fact, most studies on sympathetic role in this field have been performed in the submaxillary gland, and the role of the cervical sympathetic on the salivary secretion was not fully understood. The present study was aimed to investigate the effect of the cervical sympathetic stimulation on submaxillary and parotid secretion in ketamine-anesthetized cats.
Spontaneous salivary secretion was not observed from both glands. Stimulation of the cervical sympathetic produced only a scanty salivary flow from the submaxillary gland, which was gradually decreased by repetitive stimulation, whereas no salivary flow from the parotid gland. Salivary flows both from the submaxillary gland by stimulation of the chorda tympani and from the parotid gland by stimulation of the auriculotemporal nerve were only decreased by superimposed stimulation of the sympathetic with effective impulse regardless of low and high frequency.
These sympathetic effects were abolished by the pretreatment with phenoxybenzamine. Salivary flows from both glands evoked by the administration of pilocarpine were decreased either by superimposed stimulation of the cervical sympathetic or by the administration of norepinephrine, which were also abolished by the pretreatment with phenoxybenzamine.
These results indicate that the cervical sympathetic plays a role of inhibitory effect on the parotid secretion and dual effect, inhibitory and excitatory, on the submaxillary response. Inhibitory effect on both glands may be produced by decreased blood flow to the glands, and excitatory effect on the submaxillary gland seems to be caused by contractions of the contractile elements of the excretory duct.
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